Understanding protein-drug interactions using ion mobility-mass spectrometry.

Eyers, Claire E; Vonderach, Matthias; Ferries, Samantha; Jeacock, Kiani; Eyers, Patrick A

Eyers, Claire E; Vonderach, Matthias; Ferries, Samantha; Jeacock, Kiani; Eyers, Patrick A.

Afiliação

Eyers CE; Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom. Electronic address: CEyers@Liverpool.ac.uk.
Vonderach M; Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.
Ferries S; Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.
Jeacock K; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.
Eyers PA; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.

Curr Opin Chem Biol ; 42: 167-176, 2018 02.

Article em En | MEDLINE | ID: mdl-29331721

Assuntos

Proteínas Intrinsicamente Desordenadas/química; Espectrometria de Mobilidade Iônica/métodos; Espectrometria de Massas/métodos; Preparações Farmacêuticas/química; Proteínas Quinases/metabolismo; Proteínas/química; Proteínas/metabolismo; Humanos; Ligantes; Estrutura Molecular; Ligação Proteica; Conformação Proteica

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Espectrometria de Massas / Preparações Farmacêuticas / Proteínas / Proteínas Intrinsicamente Desordenadas / Espectrometria de Mobilidade Iônica Limite: Humans Idioma: En Revista: Curr Opin Chem Biol Assunto da revista: BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article

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