An Autoimmune Disease-Associated Risk Variant in the <i>TNFAIP3</i> Gene Plays a Protective Role in Brucellosis That Is Mediated by the NF-&#954;B Signaling Pathway.

Lou, Lixin; Bao, Wanguo; Liu, Xianjun; Song, Hongxiao; Wang, Yang; Zhang, Kaiyu; Gao, Wenjing; Li, Haijun; Tu, Zhengkun; Wang, Shaofeng

An Autoimmune Disease-Associated Risk Variant in the TNFAIP3 Gene Plays a Protective Role in Brucellosis That Is Mediated by the NF-κB Signaling Pathway.

Lou, Lixin; Bao, Wanguo; Liu, Xianjun; Song, Hongxiao; Wang, Yang; Zhang, Kaiyu; Gao, Wenjing; Li, Haijun; Tu, Zhengkun; Wang, Shaofeng.

Afiliação

Lou L; Department of Infectious Diseases, The First Hospital of Jilin University, Jilin, China.
Bao W; Department of Infectious Diseases, The First Hospital of Jilin University, Jilin, China.
Liu X; The Bethune Institute of Epigenetic Medicine, The First Hospital of Jilin University, Jilin, China.
Song H; Department of Translational Medicine, The First Hospital, Jilin University, Jilin, China.
Wang Y; Department of Infectious Diseases, The First Hospital of Jilin University, Jilin, China.
Zhang K; Department of Infectious Diseases, The First Hospital of Jilin University, Jilin, China.
Gao W; The Bethune Institute of Epigenetic Medicine, The First Hospital of Jilin University, Jilin, China.
Li H; Department of Translational Medicine, The First Hospital, Jilin University, Jilin, China.
Tu Z; Department of Translational Medicine, The First Hospital, Jilin University, Jilin, China tuzhengkun@hotmail.com shaofengwang@jlu.edu.cn.
Wang S; The Bethune Institute of Epigenetic Medicine, The First Hospital of Jilin University, Jilin, China tuzhengkun@hotmail.com shaofengwang@jlu.edu.cn.

J Clin Microbiol ; 56(4)2018 04.

Article em En | MEDLINE | ID: mdl-29343543

Assuntos

Doenças Autoimunes/genética; Brucelose/genética; Variação Genética; NF-kappa B/metabolismo; Proteína 3 Induzida por Fator de Necrose Tumoral alfa/genética; Animais; Doenças Autoimunes/imunologia; Brucella abortus/imunologia; Brucelose/sangue; Brucelose/imunologia; Proteínas de Ligação a DNA; Indústria de Laticínios; Feminino; Estudos de Associação Genética; Genótipo; Humanos; Interleucinas/genética; Interleucinas/imunologia; Leucócitos Mononucleares/imunologia; Leucócitos Mononucleares/microbiologia; Masculino; NF-kappa B/imunologia; Proteínas Nucleares/genética; Polimorfismo de Nucleotídeo Único/genética; Transdução de Sinais

Palavras-chave

NF-κB; TNFAIP3; brucellosis; inflammation; single nucleotide polymorphism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Variação Genética / Brucelose / NF-kappa B / Proteína 3 Induzida por Fator de Necrose Tumoral alfa Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Clin Microbiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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