Sputtered Si and Mg doped hydroxyapatite for biomedical applications.
Biomed Mater
; 13(2): 025011, 2018 01 30.
Article
em En
| MEDLINE
| ID: mdl-29381477
ABSTRACT
Hydroxyapatite (HAP) coatings are applied on metallic implant materials to combine mechanical properties of metallic material with bioactivity abilities of HAP ceramic. In this study, HAP coatings with additions of Si and Mg are proposed to be deposited on Ti6Al4V substrates by RF magnetron sputtering. Chemical bonding, morphology, topography and corrosion resistance in simulated body fluids (SBF) of the coatings were investigated. Additionally, mechanical and biological properties of the coatings were evaluated. It was found that the addition of Si and Mg does not influence the formation of a HAP phase. All the coatings exhibited smooth surface and uniform growth, without defects or cracks. Both hardness and elastic modulus of the coated samples decrease with Mg addition in the HAP-Si structure. Both Mg and Si addition into HAP coatings were found to enhance the corrosion resistance of the Ti6Al4V alloy in the SBF solution. Coatings with low Mg content exhibited better corrosion performance. All the coatings investigated were biocompatible, as demonstrated by SaOS-2 bone cell attachment and growth. However, cell proliferation and morphology were inferior on samples with the highest Mg content.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Silício
/
Durapatita
/
Materiais Revestidos Biocompatíveis
/
Magnésio
Limite:
Humans
Idioma:
En
Revista:
Biomed Mater
Assunto da revista:
ENGENHARIA BIOMEDICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Federação Russa