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Immune monitoring and TCR sequencing of CD4 T cells in a long term responsive patient with metastasized pancreatic ductal carcinoma treated with individualized, neoepitope-derived multipeptide vaccines: a case report.
Sonntag, Katja; Hashimoto, Hisayoshi; Eyrich, Matthias; Menzel, Moritz; Schubach, Max; Döcker, Dennis; Battke, Florian; Courage, Carolina; Lambertz, Helmut; Handgretinger, Rupert; Biskup, Saskia; Schilbach, Karin.
Afiliação
  • Sonntag K; Department of Pediatric Hematology and Oncology, University Children's Hospital Tübingen, Hoppe-Seyler Street 1, 72076, Tübingen, Germany.
  • Hashimoto H; Department of Pediatric Hematology and Oncology, University Children's Hospital Tübingen, Hoppe-Seyler Street 1, 72076, Tübingen, Germany.
  • Eyrich M; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University Medical Center Würzburg, Josef-Schneider Street 2, 97080, Würzburg, Germany.
  • Menzel M; Center for Genomics and Transcriptomics (CeGaT) GmbH and Practice for Human Genetics, Paul-Ehrlich-Straße 23, 72076, Tübingen, Germany.
  • Schubach M; Institute for Medical and Human Genetics, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Döcker D; Center for Genomics and Transcriptomics (CeGaT) GmbH and Practice for Human Genetics, Paul-Ehrlich-Straße 23, 72076, Tübingen, Germany.
  • Battke F; Center for Genomics and Transcriptomics (CeGaT) GmbH and Practice for Human Genetics, Paul-Ehrlich-Straße 23, 72076, Tübingen, Germany.
  • Courage C; Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00014, Helsinki, Finland.
  • Lambertz H; Klinikum Garmisch-Partenkirchen GmbH, Zentrum für Innere Medizin, 82467, Garmisch-Partenkirchen, Germany.
  • Handgretinger R; Department of Pediatric Hematology and Oncology, University Children's Hospital Tübingen, Hoppe-Seyler Street 1, 72076, Tübingen, Germany.
  • Biskup S; Center for Genomics and Transcriptomics (CeGaT) GmbH and Practice for Human Genetics, Paul-Ehrlich-Straße 23, 72076, Tübingen, Germany.
  • Schilbach K; Department of Pediatric Hematology and Oncology, University Children's Hospital Tübingen, Hoppe-Seyler Street 1, 72076, Tübingen, Germany. Karin.Schilbach@med.uni-tuebingen.de.
J Transl Med ; 16(1): 23, 2018 02 06.
Article em En | MEDLINE | ID: mdl-29409514
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Linfócitos T CD4-Positivos / Monitorização Imunológica / Receptores de Antígenos de Linfócitos T alfa-beta / Vacinas Anticâncer / Carcinoma Ductal Pancreático / Vacinas de Subunidades Antigênicas / Epitopos Limite: Humans / Male / Middle aged Idioma: En Revista: J Transl Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Linfócitos T CD4-Positivos / Monitorização Imunológica / Receptores de Antígenos de Linfócitos T alfa-beta / Vacinas Anticâncer / Carcinoma Ductal Pancreático / Vacinas de Subunidades Antigênicas / Epitopos Limite: Humans / Male / Middle aged Idioma: En Revista: J Transl Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido