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Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] using mixture-based combinatorial libraries.
Tran, Tung; Chiem, Kevin; Jani, Saumya; Arivett, Brock A; Lin, David L; Lad, Rupali; Jimenez, Verónica; Farone, Mary B; Debevec, Ginamarie; Santos, Radleigh; Giulianotti, Marc; Pinilla, Clemencia; Tolmasky, Marcelo E.
Afiliação
  • Tran T; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Chiem K; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Jani S; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Arivett BA; Department of Biology, Middle Tennessee State University, Murfreesboro, TN; Department of Chemistry, Middle Tennessee State University, Murfreesboro, TN.
  • Lin DL; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Lad R; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Jimenez V; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA.
  • Farone MB; Department of Biology, Middle Tennessee State University, Murfreesboro, TN.
  • Debevec G; Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL.
  • Santos R; Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL.
  • Giulianotti M; Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL.
  • Pinilla C; Torrey Pines Institute for Molecular Studies, San Diego, CA. Electronic address: pinilla@tpims.org.
  • Tolmasky ME; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA. Electronic address: mtolmasky@fullerton.edu.
Int J Antimicrob Agents ; 51(5): 752-761, 2018 May.
Article em En | MEDLINE | ID: mdl-29410367

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetiltransferases / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Antibacterianos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Antimicrob Agents Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetiltransferases / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Antibacterianos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Antimicrob Agents Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá País de publicação: Holanda