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Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity.
Steinhardt, James J; Guenaga, Javier; Turner, Hannah L; McKee, Krisha; Louder, Mark K; O'Dell, Sijy; Chiang, Chi-I; Lei, Lin; Galkin, Andrey; Andrianov, Alexander K; A Doria-Rose, Nicole; Bailer, Robert T; Ward, Andrew B; Mascola, John R; Li, Yuxing.
Afiliação
  • Steinhardt JJ; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, 20850, USA.
  • Guenaga J; Virology Program at the University of Maryland, College Park, MD, 20740, USA.
  • Turner HL; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, 92037, USA.
  • McKee K; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA.
  • Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Chiang CI; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Lei L; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, 20850, USA.
  • Galkin A; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, 20850, USA.
  • Andrianov AK; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, 20850, USA.
  • A Doria-Rose N; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
  • Bailer RT; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, 20850, USA.
  • Ward AB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Li Y; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA.
Nat Commun ; 9(1): 877, 2018 02 28.
Article em En | MEDLINE | ID: mdl-29491415
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Desenho de Fármacos / Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Desenho de Fármacos / Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido