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Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.
Gale, Davina; Lawson, Andrew R J; Howarth, Karen; Madi, Mikidache; Durham, Bradley; Smalley, Sarah; Calaway, John; Blais, Shannon; Jones, Greg; Clark, James; Dimitrov, Peter; Pugh, Michelle; Woodhouse, Samuel; Epstein, Michael; Fernandez-Gonzalez, Ana; Whale, Alexandra S; Huggett, Jim F; Foy, Carole A; Jones, Gerwyn M; Raveh-Amit, Hadas; Schmitt, Karin; Devonshire, Alison; Green, Emma; Forshew, Tim; Plagnol, Vincent; Rosenfeld, Nitzan.
Afiliação
  • Gale D; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Lawson ARJ; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Howarth K; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Madi M; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Durham B; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Smalley S; Inivata Inc, Research Triangle Park, NC, United States of America.
  • Calaway J; Inivata Inc, Research Triangle Park, NC, United States of America.
  • Blais S; Inivata Inc, Research Triangle Park, NC, United States of America.
  • Jones G; Inivata Inc, Research Triangle Park, NC, United States of America.
  • Clark J; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Dimitrov P; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Pugh M; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Woodhouse S; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Epstein M; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Fernandez-Gonzalez A; LGC, Teddington, Middlesex, United Kingdom.
  • Whale AS; LGC, Teddington, Middlesex, United Kingdom.
  • Huggett JF; LGC, Teddington, Middlesex, United Kingdom.
  • Foy CA; School of Biosciences & Medicine, Faculty of Health & Medical Science, University of Surrey, Guildford, United Kingdom.
  • Jones GM; LGC, Teddington, Middlesex, United Kingdom.
  • Raveh-Amit H; LGC, Teddington, Middlesex, United Kingdom.
  • Schmitt K; Horizon Discovery, Waterbeach, Cambridge, United Kingdom.
  • Devonshire A; Horizon Discovery, Waterbeach, Cambridge, United Kingdom.
  • Green E; LGC, Teddington, Middlesex, United Kingdom.
  • Forshew T; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Plagnol V; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
  • Rosenfeld N; Inivata Ltd, Granta Park, Cambridge, United Kingdom.
PLoS One ; 13(3): e0194630, 2018.
Article em En | MEDLINE | ID: mdl-29547634
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Mutacional de DNA / Biomarcadores Tumorais / Ácidos Nucleicos Livres / Mutação / Células Neoplásicas Circulantes / Neoplasias Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Mutacional de DNA / Biomarcadores Tumorais / Ácidos Nucleicos Livres / Mutação / Células Neoplásicas Circulantes / Neoplasias Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos