[Action of amsidine on the evolution of lymphocyte cultures and on the structure of human metaphase chromosomes]. / Action de l'amsidine sur l'évolution de cultures lymphocytaires et sur la structure des chromosomes métaphasiques humains.

ABSTRACT

Chromosomic alterations can be observed after the effect of a antimitotic amsidine on metaphases of cultured human lymphocytes gaps, breaks, exchange figures, deletions, rings. Moreover we notice, among these cells, particular lines of big sized lymphoplasmocytoid cells, whose rate is abnormally high when compared to reference cultures.