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ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors.
Guerrero-Zotano, Angel L; Stricker, Thomas P; Formisano, Luigi; Hutchinson, Katherine E; Stover, Daniel G; Lee, Kyung-Min; Schwarz, Luis J; Giltnane, Jennifer M; Estrada, Monica V; Jansen, Valerie M; Servetto, Alberto; Gavilá, Joaquín; Perez-Fidalgo, J Alejandro; Lluch, Ana; Llombart-Cussac, Antonio; Bayar, Mohamed Amine; Michiels, Stefan; André, Fabrice; Arnedos, Mónica; Guillem, Vicente; Ruiz-Simon, Amparo; Arteaga, Carlos L.
Afiliação
  • Guerrero-Zotano AL; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Stricker TP; Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Formisano L; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Hutchinson KE; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Stover DG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Lee KM; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Schwarz LJ; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Giltnane JM; Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Estrada MV; Breast Cancer Program, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Jansen VM; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Servetto A; Departments of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Gavilá J; Department of Medical Oncology, Instituto Valenciano de Oncología, Valencia, Spain.
  • Perez-Fidalgo JA; Department of Oncology and Hematology, Hospital ClinicoUniversitario, INCLIVA Biomedical Research Institute, University of Valencia, CIBERONC, Valencia, Spain.
  • Lluch A; Department of Oncology and Hematology, Hospital ClinicoUniversitario, INCLIVA Biomedical Research Institute, University of Valencia, CIBERONC, Valencia, Spain.
  • Llombart-Cussac A; Department of Medical Oncology, Hospital Arnau de Vilanova, Valencia, Spain.
  • Bayar MA; Service de Biostatistique et d'Epidémiologie, Gustave Roussy, Villejuif, France.
  • Michiels S; CESP, Faculté de Médecine, Université Paris Sud, Faculté de Médecine UVSQ, INSERM, Université Paris Saclay, Villejuif, France.
  • André F; Service de Biostatistique et d'Epidémiologie, Gustave Roussy, Villejuif, France.
  • Arnedos M; CESP, Faculté de Médecine, Université Paris Sud, Faculté de Médecine UVSQ, INSERM, Université Paris Saclay, Villejuif, France.
  • Guillem V; Department of Medical Oncology, Université Paris-Saclay, Gustave Roussy Cancer Campus, Villejuif, France.
  • Ruiz-Simon A; Department of Medical Oncology, Université Paris-Saclay, Gustave Roussy Cancer Campus, Villejuif, France.
  • Arteaga CL; Department of Medical Oncology, Instituto Valenciano de Oncología, Valencia, Spain.
Clin Cancer Res ; 24(11): 2517-2529, 2018 06 01.
Article em En | MEDLINE | ID: mdl-29581135
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptores de Estrogênio / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Fator de Transcrição E2F4 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptores de Estrogênio / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Fator de Transcrição E2F4 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos