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Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.
Raffield, Laura M; Ulirsch, Jacob C; Naik, Rakhi P; Lessard, Samuel; Handsaker, Robert E; Jain, Deepti; Kang, Hyun M; Pankratz, Nathan; Auer, Paul L; Bao, Erik L; Smith, Joshua D; Lange, Leslie A; Lange, Ethan M; Li, Yun; Thornton, Timothy A; Young, Bessie A; Abecasis, Goncalo R; Laurie, Cathy C; Nickerson, Deborah A; McCarroll, Steven A; Correa, Adolfo; Wilson, James G; Lettre, Guillaume; Sankaran, Vijay G; Reiner, Alex P.
Afiliação
  • Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Ulirsch JC; Division of Hematology/Oncology, The Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Naik RP; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Lessard S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Handsaker RE; Hematology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Jain D; Department of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Kang HM; Montreal Heart Institute, Montréal, Quebec, Canada.
  • Pankratz N; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Auer PL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Bao EL; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Smith JD; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
  • Lange LA; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Lange EM; Department of Laboratory Medicine & Pathology, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America.
  • Li Y; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America.
  • Thornton TA; Division of Hematology/Oncology, The Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Young BA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Abecasis GR; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Laurie CC; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.
  • Nickerson DA; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America.
  • McCarroll SA; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America.
  • Correa A; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Wilson JG; Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Lettre G; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Sankaran VG; Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
  • Reiner AP; Seattle Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America.
PLoS Genet ; 14(3): e1007293, 2018 03.
Article em En | MEDLINE | ID: mdl-29590102
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traço Falciforme / Hemoglobina Falciforme / Alfa-Globinas / Anemia Falciforme Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traço Falciforme / Hemoglobina Falciforme / Alfa-Globinas / Anemia Falciforme Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos