Familial history of hypertension as a predictor of increased arterial stiffness in normotensive offspring.
Egypt Heart J
; 69(1): 37-44, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-29622953
ABSTRACT
BACKGROUND:
Increased arterial stiffness can be used as a prognostic marker of arterial hypertension. The relationship between arterial stiffness and arterial hypertension seems to be reciprocal.OBJECTIVE:
Evaluation of changes of the arterial elastic prosperities in normotensive subjects, with and without parental history of hypertension. SUBJECTS ANDMETHODS:
One hundred and ten normotensive individuals, aged 20-30 years, were divided into two groups group-A (n = 57) and group-B (n = 53) subjects with positive and negative parental history of hypertension, respectively. Systolic, diastolic and pulse pressures were measured using mercury sphygmomanometer. The elastic properties of the ascending aorta and the common carotid arteries were assessed using M-mode echo and B-mode imaging, respectively. Stiffness index of the digital volume pulse (SIDVP) was measured in the right index finger using photoplethysmography.RESULTS:
Group A subjects showed higher aortic stiffness index (p = 0.002), carotid stiffness index (p = 0.001), carotid pulse wave velocity (p ⩽ 0.001) and stiffness index of digital volume pulse (p = 0.001). Group A subjects showed lower aortic distensibility (p = 0.001), aortic strain (p = 0.004), changes in aortic diameter (p = 0.022), carotid distension (p = 0.026), carotid distensibility coefficient (p ⩽ 0.001) and carotid compliance coefficient (p = 0.002).CONCLUSION:
The aortic and carotid stiffness parameters and SIDVP were higher in normotensive offspring of hypertensive parents. This finding could direct the attention towards the increased cardiovascular risk in this group and thus prompt earlier and tighter prevention of cardiovascular risk factors.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Egypt Heart J
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Egito