Histochemical localization of carbonic anhydrase in normal and diseased human muscle.
Muscle Nerve
; 11(2): 108-13, 1988 Feb.
Article
em En
| MEDLINE
| ID: mdl-2963957
ABSTRACT
A method is described for histological localization of carbonic anhydrase (CA) in sections of frozen human muscle using the rapid and inexpensive histochemical technique of Hansson. Results obtained in normal subjects indicate clearly that CA reactive fibers are of type 1. Similarly, abnormalities seen with CA in the muscle biopsy of a patient presenting with type 1 fiber hypotrophy and preponderance duplicated almost exactly those observed with the actinomyosine adenosine triphosphatase and the reduced nicotinamide adenine dinucleotide dehydrogenase reactions. Observations of grouped CA-positive muscle fibers in a case of chronic neurogenic atrophy suggest that, like other enzymes, CA expression in muscle is under neurogenic control.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anidrases Carbônicas
/
Músculos
/
Doenças Musculares
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Muscle Nerve
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Canadá