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Targeting GLP-1 receptor trafficking to improve agonist efficacy.
Jones, Ben; Buenaventura, Teresa; Kanda, Nisha; Chabosseau, Pauline; Owen, Bryn M; Scott, Rebecca; Goldin, Robert; Angkathunyakul, Napat; Corrêa, Ivan R; Bosco, Domenico; Johnson, Paul R; Piemonti, Lorenzo; Marchetti, Piero; Shapiro, A M James; Cochran, Blake J; Hanyaloglu, Aylin C; Inoue, Asuka; Tan, Tricia; Rutter, Guy A; Tomas, Alejandra; Bloom, Stephen R.
Afiliação
  • Jones B; Section of Investigative Medicine, Imperial College London, London, W12 0NN, UK.
  • Buenaventura T; Section of Cell Biology and Functional Genomics, Imperial College London, London, W12 0NN, UK.
  • Kanda N; Section of Cell Biology and Functional Genomics, Imperial College London, London, W12 0NN, UK.
  • Chabosseau P; Section of Cell Biology and Functional Genomics, Imperial College London, London, W12 0NN, UK.
  • Owen BM; Section of Investigative Medicine, Imperial College London, London, W12 0NN, UK.
  • Scott R; Section of Investigative Medicine, Imperial College London, London, W12 0NN, UK.
  • Goldin R; Centre for Pathology, Imperial College London, London, W2 1NY, UK.
  • Angkathunyakul N; Centre for Pathology, Imperial College London, London, W2 1NY, UK.
  • Corrêa IR; Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
  • Bosco D; New England Biolabs, Inc., Ipswich, 01938, MA, USA.
  • Johnson PR; Department of Surgery, University of Geneva, Geneva, CH-1211, Switzerland.
  • Piemonti L; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, OX3 9DU, UK.
  • Marchetti P; Diabetes Research Institute (HSR-DRI), San Raffaele Scientific Institute, Milan, 20132, Italy.
  • Shapiro AMJ; Vita-Salute San Raffaele University, Milan, 20132, Italy.
  • Cochran BJ; Department of Clinical and Experimental Medicine, Islet Cell Laboratory, University of Pisa, Pisa, 56124, Italy.
  • Hanyaloglu AC; Clinical Islet Laboratory and Clinical Islet Transplant Program, University of Alberta, Edmonton, T6G 2C8, AB, Canada.
  • Inoue A; Section of Renal and Vascular Inflammation, Imperial College London, London, W12 0NN, UK.
  • Tan T; School of Medical Sciences, UNSW Sydney, Sydney, 2052, NSW, Australia.
  • Rutter GA; Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK.
  • Tomas A; Tohoku University, Sendai, 980-8574, Japan.
  • Bloom SR; Section of Investigative Medicine, Imperial College London, London, W12 0NN, UK.
Nat Commun ; 9(1): 1602, 2018 04 23.
Article em En | MEDLINE | ID: mdl-29686402

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes / Insulina Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes / Insulina Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido