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Gut microbiomes of wild great apes fluctuate seasonally in response to diet.
Hicks, Allison L; Lee, Kerry Jo; Couto-Rodriguez, Mara; Patel, Juber; Sinha, Rohini; Guo, Cheng; Olson, Sarah H; Seimon, Anton; Seimon, Tracie A; Ondzie, Alain U; Karesh, William B; Reed, Patricia; Cameron, Kenneth N; Lipkin, W Ian; Williams, Brent L.
Afiliação
  • Hicks AL; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Lee KJ; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Couto-Rodriguez M; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Patel J; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Sinha R; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Guo C; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Olson SH; Wildlife Conservation Society, Wildlife Health Program, Bronx, NY, 10460, USA.
  • Seimon A; Department of Geography and Planning, Appalachian State University, Boone, NC, 28608, USA.
  • Seimon TA; Center for Infection and Immunity, Columbia University, New York, NY, 10032, USA.
  • Ondzie AU; Wildlife Conservation Society, Zoological Health Program, Bronx, NY, 10460, USA.
  • Karesh WB; Wildlife Conservation Society, Wildlife Health Program, Bronx, NY, 10460, USA.
  • Reed P; Wildlife Conservation Society, Global Health Program, Bronx, NY, 10460, USA.
  • Cameron KN; EcoHealth Alliance, New York, NY, 10001, USA.
  • Lipkin WI; Wildlife Conservation Society, Wildlife Health Program, Bronx, NY, 10460, USA.
  • Williams BL; Wildlife Conservation Society, Wildlife Health Program, Bronx, NY, 10460, USA.
Nat Commun ; 9(1): 1786, 2018 05 03.
Article em En | MEDLINE | ID: mdl-29725011
The microbiome is essential for extraction of energy and nutrition from plant-based diets and may have facilitated primate adaptation to new dietary niches in response to rapid environmental shifts. Here we use 16S rRNA sequencing to characterize the microbiota of wild western lowland gorillas and sympatric central chimpanzees and demonstrate compositional divergence between the microbiotas of gorillas, chimpanzees, Old World monkeys, and modern humans. We show that gorilla and chimpanzee microbiomes fluctuate with seasonal rainfall patterns and frugivory. Metagenomic sequencing of gorilla microbiomes demonstrates distinctions in functional metabolic pathways, archaea, and dietary plants among enterotypes, suggesting that dietary seasonality dictates shifts in the microbiome and its capacity for microbial plant fiber digestion versus growth on mucus glycans. These data indicate that great ape microbiomes are malleable in response to dietary shifts, suggesting a role for microbiome plasticity in driving dietary flexibility, which may provide fundamental insights into the mechanisms by which diet has driven the evolution of human gut microbiomes.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estações do Ano / Cercopithecidae / Pan troglodytes / Dieta / Microbioma Gastrointestinal / Gorilla gorilla Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estações do Ano / Cercopithecidae / Pan troglodytes / Dieta / Microbioma Gastrointestinal / Gorilla gorilla Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido