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A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.
Mele, Luigi; Paino, Francesca; Papaccio, Federica; Regad, Tarik; Boocock, David; Stiuso, Paola; Lombardi, Angela; Liccardo, Davide; Aquino, Gabriella; Barbieri, Antonio; Arra, Claudio; Coveney, Clare; La Noce, Marcella; Papaccio, Gianpaolo; Caraglia, Michele; Tirino, Virginia; Desiderio, Vincenzo.
Afiliação
  • Mele L; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Paino F; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Papaccio F; Oncologia Medica ed Ematologia, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara", University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Regad T; The John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, NG1 4FQ, Nottingham, UK.
  • Boocock D; The John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, NG1 4FQ, Nottingham, UK.
  • Stiuso P; Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Lombardi A; Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Liccardo D; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Aquino G; Department of Research, Pathology Unit, Istituto Nazionale Tumori- IRCCS- Fondazione Pascale, 80131, Naples, Italy.
  • Barbieri A; SSD Sperimentazione Animale, Istituto Nazionale Tumori- IRCCS- Fondazione Pascale, 80131, Naples, Italy.
  • Arra C; SSD Sperimentazione Animale, Istituto Nazionale Tumori- IRCCS- Fondazione Pascale, 80131, Naples, Italy.
  • Coveney C; The John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, NG1 4FQ, Nottingham, UK.
  • La Noce M; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Papaccio G; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy. gianpaolo.papaccio@unicampania.it.
  • Caraglia M; Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy. michele.caraglia@unicampania.it.
  • Tirino V; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
  • Desiderio V; Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy.
Cell Death Dis ; 9(5): 572, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29760380
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Via de Pentose Fosfato / Estilbenos / Pontos de Checagem da Fase S do Ciclo Celular / Glucosefosfato Desidrogenase / Glucosídeos / Proteínas de Neoplasias / Neoplasias Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Via de Pentose Fosfato / Estilbenos / Pontos de Checagem da Fase S do Ciclo Celular / Glucosefosfato Desidrogenase / Glucosídeos / Proteínas de Neoplasias / Neoplasias Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália País de publicação: Reino Unido