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Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.
Dehmel, Stefan; Nathan, Petra; Bartel, Sabine; El-Merhie, Natalia; Scherb, Hagen; Milger, Katrin; John-Schuster, Gerrit; Yildirim, Ali Oender; Hylkema, Machteld; Irmler, Martin; Beckers, Johannes; Schaub, Bianca; Eickelberg, Oliver; Krauss-Etschmann, Susanne.
Afiliação
  • Dehmel S; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany.
  • Nathan P; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany.
  • Bartel S; Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany.
  • El-Merhie N; Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany.
  • Scherb H; Institute of Computational Biology, Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health, Neuherberg, Germany.
  • Milger K; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany.
  • John-Schuster G; Department of Internal Medicine V, University of Munich (LMU), Munich, Germany.
  • Yildirim AO; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany.
  • Hylkema M; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany.
  • Irmler M; Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
  • Beckers J; Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany.
  • Schaub B; Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany.
  • Eickelberg O; Chair of Experimental Genetics, Technische Universität München, Freising, Germany.
  • Krauss-Etschmann S; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Sci Rep ; 8(1): 7547, 2018 05 15.
Article em En | MEDLINE | ID: mdl-29765129
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Poluição por Fumaça de Tabaco / Fator de Crescimento Insulin-Like I / Exposição Materna / Perfilação da Expressão Gênica / Pulmão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Child / Female / Humans / Male / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Poluição por Fumaça de Tabaco / Fator de Crescimento Insulin-Like I / Exposição Materna / Perfilação da Expressão Gênica / Pulmão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Child / Female / Humans / Male / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido