High birth weight was associated with increased radial artery intima thickness but not with other investigated cardiovascular risk factors in adulthood.
Acta Paediatr
; 107(12): 2152-2157, 2018 12.
Article
em En
| MEDLINE
| ID: mdl-29791055
ABSTRACT
AIM:
This study investigated whether a high birth weight was associated with increased risk factors for cardiovascular disease when Swedish adults reached 34-40.METHODS:
We studied 27 subjects born at Uppsala University Hospital in 1975-1979, weighing at least 4500 g, and compared them with 27 controls selected by the Swedish National Board of Welfare with birth weights within ±1 standard deviations scores and similar ages and gender. The study included body mass index (BMI), blood pressure, lipid profile, haemoglobin A1c (HbA1c), C-reactive protein (CRP) and high-frequency ultrasound measurements of intima-media thickness, intima thickness (IT) and intimamedia ratio of the carotid and radial arteries.RESULTS:
Subjects with a high birth weight did not differ from controls with regard to BMI, blood pressure, lipid profile, high-sensitivity CRP, HbA1c or carotid artery wall dimensions. However, their radial artery intima thickness was 37% greater than the control group and their intimamedia ratio was 44% higher.CONCLUSION:
Our findings indicate that a high birth weight was associated with increased radial artery intima thickness, but not with other investigated cardiovascular risk factors, at 34-40 years of age. The clinical implications of these findings should be investigated further, especially in subjects born with a very high birth weight.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peso ao Nascer
/
Doenças Cardiovasculares
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Artéria Radial
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Espessura Intima-Media Carotídea
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Female
/
Humans
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Male
Idioma:
En
Revista:
Acta Paediatr
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Suécia