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Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Yang, Shu; Xu, Miao; Lee, Emily M; Gorshkov, Kirill; Shiryaev, Sergey A; He, Shihua; Sun, Wei; Cheng, Yu-Shan; Hu, Xin; Tharappel, Anil Mathew; Lu, Billy; Pinto, Antonella; Farhy, Chen; Huang, Chun-Teng; Zhang, Zirui; Zhu, Wenjun; Wu, Yuying; Zhou, Yi; Song, Guang; Zhu, Heng; Shamim, Khalida; Martínez-Romero, Carles; García-Sastre, Adolfo; Preston, Richard A; Jayaweera, Dushyantha T; Huang, Ruili; Huang, Wenwei; Xia, Menghang; Simeonov, Anton; Ming, Guoli; Qiu, Xiangguo; Terskikh, Alexey V; Tang, Hengli; Song, Hongjun; Zheng, Wei.
Afiliação
  • Yang S; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Xu M; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Lee EM; 2Department of Biological Science, Florida State University, Tallahassee, FL 32306 USA.
  • Gorshkov K; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Shiryaev SA; 3Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
  • He S; 4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2 Canada.
  • Sun W; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Cheng YS; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Hu X; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Tharappel AM; 2Department of Biological Science, Florida State University, Tallahassee, FL 32306 USA.
  • Lu B; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Pinto A; 3Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
  • Farhy C; 3Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
  • Huang CT; 3Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
  • Zhang Z; 4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2 Canada.
  • Zhu W; 4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2 Canada.
  • Wu Y; 5Department of Biomedical Sciences, Florida State University, Tallahassee, FL 32306 USA.
  • Zhou Y; 5Department of Biomedical Sciences, Florida State University, Tallahassee, FL 32306 USA.
  • Song G; 6Department of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD USA.
  • Zhu H; 6Department of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD USA.
  • Shamim K; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Martínez-Romero C; 7Department of Microbiology and Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • García-Sastre A; 7Department of Microbiology and Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Preston RA; 8Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136 USA.
  • Jayaweera DT; 8Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136 USA.
  • Huang R; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Huang W; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Xia M; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Simeonov A; 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892 USA.
  • Ming G; 9Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104 USA.
  • Qiu X; 4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2 Canada.
  • Terskikh AV; 10Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba R3E 0J9 Canada.
  • Tang H; 3Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
  • Song H; 2Department of Biological Science, Florida State University, Tallahassee, FL 32306 USA.
  • Zheng W; 9Department of Neuroscience and Mahoney Institute for Neurosciences, University of Pennsylvania, Philadelphia, PA 19104 USA.
Cell Discov ; 4: 31, 2018.
Article em En | MEDLINE | ID: mdl-29872540

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cell Discov Ano de publicação: 2018 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cell Discov Ano de publicação: 2018 Tipo de documento: Article País de publicação: Reino Unido