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Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning.
Sips, Patrick Y; Shi, Xu; Musso, Gabriel; Nath, Anjali K; Zhao, Yanbin; Nielson, Jason; Morningstar, Jordan; Kelly, Amy E; Mikell, Brittney; Buys, Eva; Bebarta, Vikhyat; Rutter, Jared; Davisson, V Jo; Mahon, Sari; Brenner, Matthew; Boss, Gerry R; Peterson, Randall T; Gerszten, Robert E; MacRae, Calum A.
Afiliação
  • Sips PY; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Shi X; Center for Medical Genetics Ghent, Department of Pediatrics and Medical Genetics, Ghent University, Ghent, Belgium.
  • Musso G; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, United States of America.
  • Nath AK; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Zhao Y; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, United States of America.
  • Nielson J; Division of Cardiology, Department of Medicine, Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, United States of America.
  • Morningstar J; Broad Institute, Cambridge, United States of America.
  • Kelly AE; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Mikell B; Broad Institute, Cambridge, United States of America.
  • Buys E; Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, United States of America.
  • Bebarta V; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, United States of America.
  • Rutter J; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Davisson VJ; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Mahon S; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America.
  • Brenner M; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, United States of America.
  • Boss GR; Department of Biochemistry and Howard Hughes Medical Institute, University of Utah, Salt Lake City, United States of America.
  • Peterson RT; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue College of Pharmacy, West Lafayette, United States of America.
  • Gerszten RE; Department of Medicine, Beckman Laser Institute, University of California, Irvine, United States of America.
  • MacRae CA; Department of Medicine, Beckman Laser Institute, University of California, Irvine, United States of America.
PLoS One ; 13(6): e0193889, 2018.
Article em En | MEDLINE | ID: mdl-29879736
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cianeto de Potássio / Complexo Piruvato Desidrogenase / Peixe-Zebra / Proteínas de Peixe-Zebra / Metaboloma / Metabolômica Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cianeto de Potássio / Complexo Piruvato Desidrogenase / Peixe-Zebra / Proteínas de Peixe-Zebra / Metaboloma / Metabolômica Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos