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Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.
Ruuth, Maija; Nguyen, Su Duy; Vihervaara, Terhi; Hilvo, Mika; Laajala, Teemu D; Kondadi, Pradeep Kumar; Gisterå, Anton; Lähteenmäki, Hanna; Kittilä, Tiia; Huusko, Jenni; Uusitupa, Matti; Schwab, Ursula; Savolainen, Markku J; Sinisalo, Juha; Lokki, Marja-Liisa; Nieminen, Markku S; Jula, Antti; Perola, Markus; Ylä-Herttula, Seppo; Rudel, Lawrence; Öörni, Anssi; Baumann, Marc; Baruch, Amos; Laaksonen, Reijo; Ketelhuth, Daniel F J; Aittokallio, Tero; Jauhiainen, Matti; Käkelä, Reijo; Borén, Jan; Williams, Kevin Jon; Kovanen, Petri T; Öörni, Katariina.
Afiliação
  • Ruuth M; Atherosclerosis Research Laboratory, Wihuri Research Institute, Haartmaninkatu 8, 00290 Helsinki, Finland.
  • Nguyen SD; Research Programs Unit, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, P.O. Box 63, 00014 University of Helsinki, Finland.
  • Vihervaara T; Atherosclerosis Research Laboratory, Wihuri Research Institute, Haartmaninkatu 8, 00290 Helsinki, Finland.
  • Hilvo M; Zora Biosciences, Biologinkuja 1, 02150 Espoo, Finland.
  • Laajala TD; Zora Biosciences, Biologinkuja 1, 02150 Espoo, Finland.
  • Kondadi PK; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Tukholmankatu 8, P.O. Box 20, 00014 University of Helsinki, Finland.
  • Gisterå A; Department of Mathematics and Statistics, University of Turku, Vesilinnantie 5, 20014 University of Turku, Finland.
  • Lähteenmäki H; Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, SU Sahlgrenska, 41345 Gothenburg, Sweden.
  • Kittilä T; Department of Medicine, Karolinska University Hospital, Karolinska Institute, Solna 171 76 Stockholm, Sweden.
  • Huusko J; Atherosclerosis Research Laboratory, Wihuri Research Institute, Haartmaninkatu 8, 00290 Helsinki, Finland.
  • Uusitupa M; Atherosclerosis Research Laboratory, Wihuri Research Institute, Haartmaninkatu 8, 00290 Helsinki, Finland.
  • Schwab U; Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Yliopistonranta 1, P.O. Box 1627, 70211 Kuopio, Finland.
  • Savolainen MJ; Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Yliopistonranta 1, P.O. Box 1627, 70211 Kuopio, Finland.
  • Sinisalo J; Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Yliopistonranta 1, P.O. Box 1627, 70211 Kuopio, Finland.
  • Lokki ML; Institute of Clinical Medicine, Internal Medicine, Kuopio University Hospital, Puijonlaaksontie 2, P.O. Box 100, 70029 Kuopio, Finland.
  • Nieminen MS; Research Unit of Internal Medicine, University of Oulu, Pentti Kaiteran katu 1, P.O. Box 8000, 90014, Oulu, Finland.
  • Jula A; Medical Research Center, Oulu University Hospital, Pentti Kaiteran katu 1, P.O. Box 8000, 90014 Oulu, Finland.
  • Perola M; Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, P.O. Box 340, 00029 Helsinki, Finland.
  • Ylä-Herttula S; Transplantation Laboratory, Medicum, University of Helsinki, Haartmaninkatu 3, P.O. Box 21, 00014 Helsinki, Finland.
  • Rudel L; Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, P.O. Box 340, 00029 Helsinki, Finland.
  • Öörni A; Genomics and Biomarkers Unit, Department of Health, National Institute for Health and Welfare, Genomics and Biomarkers Unit, Mannerheimintie 166, P.O. Box 30, 00271 Helsinki, Finland.
  • Baumann M; Genomics and Biomarkers Unit, Department of Health, National Institute for Health and Welfare, Genomics and Biomarkers Unit, Mannerheimintie 166, P.O. Box 30, 00271 Helsinki, Finland.
  • Baruch A; Institute for Molecular Medicine Finland and Diabetes and Obesity Research Program, University of Helsinki, Haartmaninkatu 8, P.O. Box 63, 00014 University of Helsinki, Finland.
  • Laaksonen R; Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Yliopistonranta 1, P.O. Box 1627, 70211 Kuopio, Finland.
  • Ketelhuth DFJ; Heart Center and Gene Therapy Unit, Kuopio University Hospital, Puijonlaaksontie 2, P.O. Box 100, 70029 Kuopio, Finland.
  • Aittokallio T; Department of Biochemistry Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
  • Jauhiainen M; Information Systems, Åbo Akademi University, Fänriksgatan 3A, 20500 Turku, Finland.
  • Käkelä R; Meilahti Clinical Proteomics Core Facility, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, P.O. Box 63, 00014 University of Helsinki, Finland.
  • Borén J; Genentech Research and Early Development, 1 DNA Way Mailstop 258A, South San Francisco, CA 94080, USA.
  • Williams KJ; Zora Biosciences, Biologinkuja 1, 02150 Espoo, Finland.
  • Kovanen PT; Finnish Cardiovascular Research Center, University of Tampere, Kalevantie 4, 33100 Tampere, Finland.
  • Öörni K; Finnish Clinical Biobank Tampere, University Hospital of Tampere, Arvo Ylpön katu 6, 33520 Tampere, Finland.
Eur Heart J ; 39(27): 2562-2573, 2018 07 14.
Article em En | MEDLINE | ID: mdl-29982602
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Lipoproteínas LDL Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Eur Heart J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Lipoproteínas LDL Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Eur Heart J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Reino Unido