Human proto-oncogene c-mos maps to 8q11.
EMBO J
; 4(9): 2245-8, 1985 Sep.
Article
em En
| MEDLINE
| ID: mdl-3000766
ABSTRACT
The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hydridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos has been found in acute leukaemia with the chromosomal translocation t(8;21)(q22;q22).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proto-Oncogenes
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Cromossomos Humanos 6-12 e X
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Vírus do Sarcoma Murino de Moloney
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Vírus do Sarcoma Murino
Limite:
Animals
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Humans
Idioma:
En
Revista:
EMBO J
Ano de publicação:
1985
Tipo de documento:
Article