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Design and biological evaluation of novel hybrids of 1, 5-diarylpyrazole and Chrysin for selective COX-2 inhibition.
Ren, Shen-Zhen; Wang, Zhong-Chang; Zhu, Xiao-Hua; Zhu, Dan; Li, Zhang; Shen, Fa-Qian; Duan, Yong-Tao; Cao, Han; Zhao, Jing; Zhu, Hai-Liang.
Afiliação
  • Ren SZ; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Wang ZC; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Zhu XH; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Zhu D; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Li Z; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Shen FQ; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Duan YT; Henan Provincial Key Laboratory of Children's Genetics and Metabolic Diseases, Zhengzhou Children's Hospital, Zhengzhou 450018, PR China.
  • Cao H; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China.
  • Zhao J; State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210023, PR China.
  • Zhu HL; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, PR China. Electronic address: zhuhl@nju.edu.cn.
Bioorg Med Chem ; 26(14): 4264-4275, 2018 08 07.
Article em En | MEDLINE | ID: mdl-30031652
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Flavonoides / Desenho de Fármacos / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Flavonoides / Desenho de Fármacos / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Reino Unido