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Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Jain, Mukul R; Mohapatra, Jogeswar; Bandhyopadhyay, Debdutta; Chatterjee, Abhijit; Ghoshdastidar, Krishnarup; Patel, Dinesh; Patel, Ankit; Bhayani, Hitesh; Srivastava, Brijesh Kumar; Shedage, Sandeep A; Kadam, Pravin; Sundar, Rajesh; Patel, Harilal; Giri, Poonam; Patel, Prakash; Gupta, Laxmikant; Srinivas, Nuggehally R; Patel, Pankaj R; Desai, Ranjit C.
Afiliação
  • Jain MR; Department of Pharmacology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Mohapatra J; Department of Pharmacology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Bandhyopadhyay D; Department of Cell Biology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Chatterjee A; Department of Pharmacology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India. abhijitchatterjee@zyduscadila.com.
  • Ghoshdastidar K; Department of Cell Biology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Patel D; Department of Pharmacology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Patel A; Department of Cell Biology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Bhayani H; Department of Cell Biology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Srivastava BK; Department of Medicinal Chemistry, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Shedage SA; Department of Medicinal Chemistry, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Kadam P; Department of Medicinal Chemistry, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Sundar R; Department of Toxicology, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Patel H; Department of Pharmacokinetics, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Giri P; Department of Pharmacokinetics, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Patel P; Department of Pharmacokinetics, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Gupta L; Department of Pharmacokinetics, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Srinivas NR; Department of Pharmacokinetics, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
  • Patel PR; Zydus Research Centre, Cadila Healthcare Ltd, Satellite cross road, Ahmadabad, Gujarat, India.
  • Desai RC; Department of Medicinal Chemistry, Zydus Research Centre, Moraiya, Ahmadabad, Gujarat, India.
Cancer Chemother Pharmacol ; 82(4): 635-647, 2018 10.
Article em En | MEDLINE | ID: mdl-30046848
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Neoplasias do Colo / Inibidores de Poli(ADP-Ribose) Polimerases Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia País de publicação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Neoplasias do Colo / Inibidores de Poli(ADP-Ribose) Polimerases Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia País de publicação: Alemanha