The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling.

Andenæs, Kine; Lunde, Ida G; Mohammadzadeh, Naiyereh; Dahl, Christen P; Aronsen, Jan Magnus; Strand, Mari E; Palmero, Sheryl; Sjaastad, Ivar; Christensen, Geir; Engebretsen, Kristin V T; Tønnessen, Theis

Andenæs, Kine; Lunde, Ida G; Mohammadzadeh, Naiyereh; Dahl, Christen P; Aronsen, Jan Magnus; Strand, Mari E; Palmero, Sheryl; Sjaastad, Ivar; Christensen, Geir; Engebretsen, Kristin V T; Tønnessen, Theis.

Afiliação

Andenæs K; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Lunde IG; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Mohammadzadeh N; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Dahl CP; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Aronsen JM; Centre for Molecular Medicine Norway, Oslo University Hospital and University of Oslo, Oslo, Norway.
Strand ME; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Palmero S; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Sjaastad I; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Christensen G; Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.
Engebretsen KVT; Department of Cardiology, Oslo University Hospital, Oslo, Norway.
Tønnessen T; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.

PLoS One ; 13(7): e0201422, 2018.

Article em En | MEDLINE | ID: mdl-30052659

Assuntos

Cardiomegalia/metabolismo; Matriz Extracelular/metabolismo; Fibromodulina/biossíntese; Insuficiência Cardíaca/metabolismo; Miocárdio/metabolismo; Animais; Biomarcadores; Cardiomegalia/genética; Cardiomegalia/patologia; Modelos Animais de Doenças; Matriz Extracelular/genética; Matriz Extracelular/patologia; Feminino; Fibroblastos/metabolismo; Fibroblastos/patologia; Fibromodulina/genética; Insuficiência Cardíaca/genética; Insuficiência Cardíaca/patologia; Humanos; Masculino; Camundongos; Camundongos Knockout; Miocárdio/patologia; Miócitos Cardíacos/metabolismo; Miócitos Cardíacos/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomegalia / Matriz Extracelular / Fibromodulina / Insuficiência Cardíaca / Miocárdio Limite: Animals / Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Noruega País de publicação: Estados Unidos

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