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Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration.
Akiyama, Masato; Takahashi, Atsushi; Momozawa, Yukihide; Arakawa, Satoshi; Miya, Fuyuki; Tsunoda, Tatsuhiko; Ashikawa, Kyota; Oshima, Yuji; Yasuda, Miho; Yoshida, Shigeo; Enaida, Hiroshi; Tan, Xue; Yanagi, Yasuo; Yasukawa, Tsutomu; Ogura, Yuichiro; Nagai, Yoshimi; Takahashi, Kanji; Fujisawa, Kimihiko; Inoue, Maiko; Arakawa, Akira; Tanaka, Koji; Yuzawa, Mitsuko; Kadonosono, Kazuaki; Sonoda, Koh-Hei; Ishibashi, Tatsuro; Kubo, Michiaki.
Afiliação
  • Akiyama M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. masato.akiyama@riken.jp.
  • Takahashi A; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan. masato.akiyama@riken.jp.
  • Momozawa Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. masato.akiyama@riken.jp.
  • Arakawa S; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Miya F; Department of Genomic Medicine, Research Institute, National Cerebral and Cardiovascular Center, Osaka, 565-8565, Japan.
  • Tsunoda T; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Ashikawa K; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
  • Oshima Y; Japan Community Health care Organization, Kyushu Hospital, 1-8-1 Kishinoura, Yahatanishi-ku, Kitakyushu, Fukuoka, 806-0034, Japan.
  • Yasuda M; Steel Memorial Yawata Hospital, 1-1-1 Harunomachi, Yahatahigashi-ku, Kitakyushu, Fukuoka, 805-8508, Japan.
  • Yoshida S; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, 1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Enaida H; Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
  • Tan X; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, 1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Yanagi Y; Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
  • Yasukawa T; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
  • Ogura Y; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
  • Nagai Y; Department of Ophthalmology, Fukuoka University Chikushi Hospital, Fukuoka, 818-8502, Japan.
  • Takahashi K; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
  • Fujisawa K; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
  • Inoue M; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maedashi, Higashi-ku, Fukuoka, Fukuoka, 812-8582, Japan.
  • Arakawa A; Department of Ophthalmology, Saga University Faculty of Medicine, 5-1-1 Nabeshima, Saga, Saga, 849-8501, Japan.
  • Tanaka K; Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Yuzawa M; Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Kadonosono K; Singapore Eye Research Institute, Singapore, 168751, Singapore.
  • Sonoda KH; Medical Retina Department, Singapore National Eye Center, Singapore, 168751, Singapore.
  • Ishibashi T; Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.
  • Kubo M; Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.
J Hum Genet ; 63(10): 1083-1091, 2018 Oct.
Article em En | MEDLINE | ID: mdl-30054556
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Proteínas Supressoras da Sinalização de Citocina / Subunidades alfa do Canal de Potássio Ativado por Cálcio de Condutância Alta / Fatores de Transcrição Otx / Estudo de Associação Genômica Ampla / Ranibizumab / Degeneração Macular Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Hum Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Proteínas Supressoras da Sinalização de Citocina / Subunidades alfa do Canal de Potássio Ativado por Cálcio de Condutância Alta / Fatores de Transcrição Otx / Estudo de Associação Genômica Ampla / Ranibizumab / Degeneração Macular Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Hum Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido