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Synthesis of novel isoindoline-1,3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX.
Abdel-Aziz, Alaa A-M; El-Azab, Adel S; Abu El-Enin, Mohamed A; Almehizia, Abdulrahman A; Supuran, Claudiu T; Nocentini, Alessio.
Afiliação
  • Abdel-Aziz AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: almoenes@ksu.edu.sa.
  • El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia; Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
  • Abu El-Enin MA; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
  • Almehizia AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
  • Supuran CT; NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.
  • Nocentini A; NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address: alessio.nocentini@unifi.it.
Bioorg Chem ; 80: 706-713, 2018 10.
Article em En | MEDLINE | ID: mdl-30064081
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Sulfonamidas / Inibidores da Anidrase Carbônica / Isoindóis / Anidrase Carbônica IX / Hidrazonas Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Sulfonamidas / Inibidores da Anidrase Carbônica / Isoindóis / Anidrase Carbônica IX / Hidrazonas Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos