Changes in topoisomerase I activity after irradiation of lymphoid cells.
Biosci Rep
; 5(10-11): 907-12, 1985.
Article
em En
| MEDLINE
| ID: mdl-3006822
ABSTRACT
The activity of topoisomerase I in nuclear extracts increased about three-fold 5 min after gamma-irradiation (840-2500 rads) of human peripheral blood lymphocytes or cultured lymphoblastoid cells. The change may reflect modification of the enzyme by nuclear ADP-ribosyl transferase, which is known to be activated by DNA breaks.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos
/
DNA Topoisomerases Tipo I
Limite:
Humans
Idioma:
En
Revista:
Biosci Rep
Ano de publicação:
1985
Tipo de documento:
Article