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Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway.
Zhou, Wenjing; Wang, Jiwei; Qi, Qichao; Feng, Zichao; Huang, Bin; Chen, Anjing; Zhang, Di; Li, Wenjie; Zhang, Qing; Bjerkvig, Rolf; Li, Xingang; Wang, Jian.
Afiliação
  • Zhou W; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Wang J; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Qi Q; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Feng Z; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Huang B; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Chen A; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Zhang D; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Li W; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Zhang Q; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Bjerkvig R; Department of Biomedicine, K G Jebsen Brain Tumor Research Center, University of Bergen, Bergen, Norway.
  • Li X; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
  • Wang J; Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.
Cancer Med ; 7(9): 4729-4743, 2018 09.
Article em En | MEDLINE | ID: mdl-30079478
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolizinas / Fator de Crescimento Insulin-Like I / Transdução de Sinais / Glioblastoma / Fosfatidilinositol 3-Quinases / Alcaloides / Proteínas Proto-Oncogênicas c-akt / Inibidor de Quinase Dependente de Ciclina p27 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolizinas / Fator de Crescimento Insulin-Like I / Transdução de Sinais / Glioblastoma / Fosfatidilinositol 3-Quinases / Alcaloides / Proteínas Proto-Oncogênicas c-akt / Inibidor de Quinase Dependente de Ciclina p27 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos