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Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
Machiela, Mitchell J; Grünewald, Thomas G P; Surdez, Didier; Reynaud, Stephanie; Mirabeau, Olivier; Karlins, Eric; Rubio, Rebeca Alba; Zaidi, Sakina; Grossetete-Lalami, Sandrine; Ballet, Stelly; Lapouble, Eve; Laurence, Valérie; Michon, Jean; Pierron, Gaelle; Kovar, Heinrich; Gaspar, Nathalie; Kontny, Udo; González-Neira, Anna; Picci, Piero; Alonso, Javier; Patino-Garcia, Ana; Corradini, Nadège; Bérard, Perrine Marec; Freedman, Neal D; Rothman, Nathaniel; Dagnall, Casey L; Burdett, Laurie; Jones, Kristine; Manning, Michelle; Wyatt, Kathleen; Zhou, Weiyin; Yeager, Meredith; Cox, David G; Hoover, Robert N; Khan, Javed; Armstrong, Gregory T; Leisenring, Wendy M; Bhatia, Smita; Robison, Leslie L; Kulozik, Andreas E; Kriebel, Jennifer; Meitinger, Thomas; Metzler, Markus; Hartmann, Wolfgang; Strauch, Konstantin; Kirchner, Thomas; Dirksen, Uta; Morton, Lindsay M; Mirabello, Lisa; Tucker, Margaret A.
Afiliação
  • Machiela MJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU, 80337, Munich, Germany.
  • Surdez D; German Consortium for Cancer Research (DKTK), 69120, Heidelberg, Germany.
  • Reynaud S; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
  • Mirabeau O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.
  • Karlins E; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Rubio RA; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Zaidi S; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
  • Grossetete-Lalami S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.
  • Ballet S; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Lapouble E; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Laurence V; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Michon J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU, 80337, Munich, Germany.
  • Pierron G; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.
  • Kovar H; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Gaspar N; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.
  • Kontny U; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • González-Neira A; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Picci P; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
  • Alonso J; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Patino-Garcia A; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
  • Corradini N; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Bérard PM; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Freedman ND; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
  • Rothman N; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
  • Dagnall CL; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, 1090, Vienna, Austria.
  • Burdett L; Department of Oncology for Child and Adolescent, Institut Gustave Roussy, 94800, Villejuif, France.
  • Jones K; Division of Pediatric Hematology Oncology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, 52062, Aachen, Germany.
  • Manning M; Human Genotyping Unit-CeGen, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, 28029, Madrid, Spain.
  • Wyatt K; Laboratorio di Oncologia Sperimentale, Istituto Ortopedico Rizzoli di Bologna, 40136, Bologna, Italy.
  • Zhou W; Unidad de Tumores Sólidos Infantiles, Instituto de Investigación de Enfermedades Raras, Instituto de Salud Carlos III, 28220, Majadahonda, Spain.
  • Yeager M; Laboratory of Pediatrics, University of Navarra, University Clinic of Navarra, IdiSNA, 31008, Pamplona, Spain.
  • Cox DG; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, 69008, Lyon, France.
  • Hoover RN; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, 69008, Lyon, France.
  • Khan J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Armstrong GT; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Leisenring WM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Bhatia S; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Robison LL; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Kulozik AE; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Kriebel J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Meitinger T; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Metzler M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Hartmann W; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Strauch K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Kirchner T; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Dirksen U; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Morton LM; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
  • Mirabello L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Tucker MA; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Nat Commun ; 9(1): 3184, 2018 08 09.
Article em En | MEDLINE | ID: mdl-30093639
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Predisposição Genética para Doença / Perfilação da Expressão Gênica / Estudo de Associação Genômica Ampla Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Predisposição Genética para Doença / Perfilação da Expressão Gênica / Estudo de Associação Genômica Ampla Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido