Bone morphogenetic proteins and inner ear development.
J Zhejiang Univ Sci B
; 20(2): 131-145, 2019.
Article
em En
| MEDLINE
| ID: mdl-30112880
ABSTRACT
Bone morphogenetic proteins (BMPs) are the largest subfamily of the transforming growth factor-ß superfamily, and they play important roles in the development of numerous organs, including the inner ear. The inner ear is a relatively small organ but has a highly complex structure and is involved in both hearing and balance. Here, we discuss BMPs and BMP signaling pathways and then focus on the role of BMP signal pathway regulation in the development of the inner ear and the implications this has for the treatment of human hearing loss and balance dysfunction.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Morfogenéticas Ósseas
/
Orelha Interna
Limite:
Humans
Idioma:
En
Revista:
J Zhejiang Univ Sci B
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China