Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane.

Jin, Jing; Galaz-Montoya, Jesús G; Sherman, Michael B; Sun, Stella Y; Goldsmith, Cynthia S; O'Toole, Eileen T; Ackerman, Larry; Carlson, Lars-Anders; Weaver, Scott C; Chiu, Wah; Simmons, Graham

Jin, Jing; Galaz-Montoya, Jesús G; Sherman, Michael B; Sun, Stella Y; Goldsmith, Cynthia S; O'Toole, Eileen T; Ackerman, Larry; Carlson, Lars-Anders; Weaver, Scott C; Chiu, Wah; Simmons, Graham.

Afiliação

Jin J; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Pathology and Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: jjin@bloodsystems.org.
Galaz-Montoya JG; Departments of Bioengineering, Microbiology and Immunology, and Photon Science, James H. Clark Center, Stanford University, Stanford, CA 94305, USA.
Sherman MB; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Sun SY; Departments of Bioengineering, Microbiology and Immunology, and Photon Science, James H. Clark Center, Stanford University, Stanford, CA 94305, USA.
Goldsmith CS; Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
O'Toole ET; Boulder Laboratory for 3-D Electron Microscopy of Cells, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.
Ackerman L; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA.
Carlson LA; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå 901 87, Sweden.
Weaver SC; Institute for Human Infections and Immunity and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Chiu W; Departments of Bioengineering, Microbiology and Immunology, and Photon Science, James H. Clark Center, Stanford University, Stanford, CA 94305, USA.
Simmons G; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Pathology and Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: gsimmons@bloodsystems.org.

Cell Host Microbe ; 24(3): 417-428.e5, 2018 09 12.

Article em En | MEDLINE | ID: mdl-30146390

Assuntos

Anticorpos Neutralizantes/imunologia; Anticorpos Antivirais/imunologia; Membrana Celular/virologia; Febre de Chikungunya/imunologia; Febre de Chikungunya/virologia; Vírus Chikungunya/fisiologia; Liberação de Vírus; Linhagem Celular; Membrana Celular/imunologia; Vírus Chikungunya/genética; Humanos; Replicação Viral

Palavras-chave

chikungunya virus (CHIKV); cryoelectron tomography (cryoET); glycoproteins (GPs); immunoelectron microscopy (IEM); neutralizing antibodies (NAbs); nucleocapsid-like particles (NCLPs); stimulated emission depletion microscopy (STED); subtomogram averaging (STA); transmission electron microscopy (TEM); virus budding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membrana Celular / Vírus Chikungunya / Anticorpos Neutralizantes / Liberação de Vírus / Febre de Chikungunya / Anticorpos Antivirais Limite: Humans Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

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