Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus.

Luk, Anderson Dik Wai; Ni, Ke; Wu, Yuet; Lam, Kwok-Tai; Chan, Koon-Wing; Lee, Pamela P; Tu, Wenwei; Mao, Huawei; Lau, Yu Lung

Luk, Anderson Dik Wai; Ni, Ke; Wu, Yuet; Lam, Kwok-Tai; Chan, Koon-Wing; Lee, Pamela P; Tu, Wenwei; Mao, Huawei; Lau, Yu Lung.

Afiliação

Luk ADW; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Ni K; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Wu Y; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
Lam KT; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Chan KW; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Lee PP; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Tu W; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
Mao H; Shenzhen Primary Immunodeficiency Diagnostic and Therapeutic Laboratory, Department of Paediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Lau YL; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.

Front Immunol ; 9: 1826, 2018.

Article em En | MEDLINE | ID: mdl-30147693

Assuntos

Tirosina Quinase da Agamaglobulinemia/genética; Células Dendríticas/imunologia; Vírus da Influenza A Subtipo H1N1/imunologia; Interferon Tipo I/metabolismo; Interferons/metabolismo; Poliomielite/imunologia; Poliovirus/imunologia; Adulto; Agamaglobulinemia; Diferenciação Celular; Células Cultivadas; Regulação da Expressão Gênica; Doenças Genéticas Ligadas ao Cromossomo X; Humanos; Mutação/genética; Transdução de Sinais; Receptores Toll-Like/metabolismo; Adulto Jovem; Interferon lambda

Palavras-chave

H1N1 influenza virus; X-linked agammaglobulinemia; dendritic cells; innate immunity; oral poliovirus vaccine; type I interferon; type III interferon

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliomielite / Células Dendríticas / Interferon Tipo I / Interferons / Poliovirus / Vírus da Influenza A Subtipo H1N1 / Tirosina Quinase da Agamaglobulinemia Limite: Adult / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Hong Kong País de publicação: Suíça

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