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An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia.
Swaroop, Alok; Oyer, Jon A; Will, Christine M; Huang, Xiaoxiao; Yu, Wenbo; Troche, Catalina; Bulic, Marinka; Durham, Benjamin H; Wen, Qiang Jeremy; Crispino, John D; MacKerell, Alexander D; Bennett, Richard L; Kelleher, Neil L; Licht, Jonathan D.
Afiliação
  • Swaroop A; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, FL, USA.
  • Oyer JA; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Will CM; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Huang X; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Yu W; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, FL, USA.
  • Troche C; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Bulic M; Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.
  • Durham BH; Department of Molecular Biosciences, Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.
  • Wen QJ; Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, USA.
  • Crispino JD; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, FL, USA.
  • MacKerell AD; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Bennett RL; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kelleher NL; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Licht JD; Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Oncogene ; 38(5): 671-686, 2019 01.
Article em En | MEDLINE | ID: mdl-30171259
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Histona-Lisina N-Metiltransferase / Mutação de Sentido Incorreto / Reprogramação Celular / Leucemia-Linfoma Linfoblástico de Células Precursoras / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Histona-Lisina N-Metiltransferase / Mutação de Sentido Incorreto / Reprogramação Celular / Leucemia-Linfoma Linfoblástico de Células Precursoras / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido