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Severe PATCHED1 Deficiency in Cancer-Prone Gorlin Patient Cells Results in Intrinsic Radiosensitivity.
Vulin, Adeline; Sedkaoui, Melissa; Moratille, Sandra; Sevenet, Nicolas; Soularue, Pascal; Rigaud, Odile; Guibbal, Laure; Dulong, Joshua; Jeggo, Penny; Deleuze, Jean-François; Lamartine, Jérôme; Martin, Michèle T.
Afiliação
  • Vulin A; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Sedkaoui M; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Moratille S; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Sevenet N; Molecular Genetics Laboratory, Institut Bergonié/INSERM U1218, Université de Bordeaux, Bordeaux cedex, France.
  • Soularue P; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Rigaud O; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Guibbal L; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France.
  • Dulong J; Laboratory of Tissue Biology and Therapeutic Engineering, UMR5305 CNRS - Université Lyon I, Lyon Cedex 07, France.
  • Jeggo P; Genome Damage and Stability Centre, University of Sussex, Brighton, United Kingdom.
  • Deleuze JF; CNRGH, Genome Institute, CEA, DRF/IFJ, Evry, France.
  • Lamartine J; Laboratory of Tissue Biology and Therapeutic Engineering, UMR5305 CNRS - Université Lyon I, Lyon Cedex 07, France.
  • Martin MT; Laboratory of Genomics and Radiobiology of Keratinopoiesis, CEA, DRF/IFJ/iRCM, INSERM/UMR967, Université Paris-Diderot, Université Paris-Saclay, Evry, France. Electronic address: michele.martin@cea.fr.
Int J Radiat Oncol Biol Phys ; 102(2): 417-425, 2018 10 01.
Article em En | MEDLINE | ID: mdl-30191873
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Síndrome do Nevo Basocelular / Fibroblastos Associados a Câncer / Receptor Patched-1 Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Radiat Oncol Biol Phys Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Síndrome do Nevo Basocelular / Fibroblastos Associados a Câncer / Receptor Patched-1 Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Radiat Oncol Biol Phys Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos