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Predictive markers in lung cancer: a few hints for the practicing pathologist.
Barbareschi, M; Barberis, M; Buttitta, F; Doglioni, C; Fiorentino, M; Fontanini, G; Franco, R; Marchetti, A; Rossi, G; Troncone, G.
Afiliação
  • Barbareschi M; Pathology Unit, Hospital S. Chiara, Trento, Italy.
  • Barberis M; Pathology Unit, European Institute of Oncology, Milan, Italy.
  • Buttitta F; Center of Predictive Molecular Medicine, Center for Excellence on Aging and Translational Medicine, University of Chieti-Pescara, Italy.
  • Doglioni C; Pathology Department, Vita Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy.
  • Fiorentino M; Department of Pathology, Addarii Institute of Oncology, S. Orsola-Malpighi Teaching Hospital, University of Bologna, Italy.
  • Fontanini G; Division of Pathological Anatomy, Department of Surgical, Medical, Molecular Pathology and Critical Care, University of Pisa, Italy.
  • Franco R; Section of Anatomic Pathology Department of Public Health, University of Naples, Federico II, Italy.
  • Marchetti A; Center of Predictive Molecular Medicine, Center for Excellence on Aging and Translational Medicine, University of Chieti-Pescara, Italy.
  • Rossi G; Pathology Unit, Hospital S. Maria delle Croci, Azienda Romagna, Ravenna, Italy.
  • Troncone G; Pathology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Pathologica ; 110(1): 29-38, 2018 Mar.
Article em En | MEDLINE | ID: mdl-30259911
This review article highlights some important points in the evolving area of predictive biomarkers determination in non-small-cell lung cancer toward standardization of testing practices, including EGFR mutations, ALK and ROS1 rearrangements and immunohistochemical expression of PD-L1. Considerations for selecting appropriate populations for molecular testing, and emergence of other targetable molecular alterations are also discussed.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas / Carcinoma Pulmonar de Células não Pequenas / Quinase do Linfoma Anaplásico / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Pathologica Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália País de publicação: Itália
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas / Carcinoma Pulmonar de Células não Pequenas / Quinase do Linfoma Anaplásico / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Pathologica Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália País de publicação: Itália