The effect of thalidomide on arachidonic acid metabolism in human polymorphonuclear leukocytes and platelets.
Br J Dermatol
; 115(6): 677-80, 1986 Dec.
Article
em En
| MEDLINE
| ID: mdl-3026430
ABSTRACT
The effect of thalidomide on the metabolism of arachidonic acid by purified washed human platelets and polymorphonuclear leukocytes was examined. The drug was found to be without effect under the conditions used. The action of thalidomide cannot therefore be attributed to a direct inhibition of prostaglandin or leukotriene biosynthesis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talidomida
/
Plaquetas
/
Ácidos Araquidônicos
/
Neutrófilos
Limite:
Humans
Idioma:
En
Revista:
Br J Dermatol
Ano de publicação:
1986
Tipo de documento:
Article
País de publicação:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM