Study of chemical, physico-mechanical and biological properties of 4,4'-methylenebis(cyclohexyl isocyanate)-based polyurethane films.
Mater Sci Eng C Mater Biol Appl
; 93: 483-494, 2018 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-30274081
ABSTRACT
Polyurethane films were obtained in the solvent-free cycloaliphatic polyaddition process of 4,4'-methylenebis(cyclohexyl isocyanate), poly(ε-caprolactone) diol or poly(oxytetramethylene) glycol and 1,4-butanediol. Chemical structures of the polymers were confirmed by FTIR, NMR and GPC methods. Their surface, thermal and mechanical properties have been evaluated. Results of biological studies with polyurethane films as potential biomaterials for medical applications revealed their mild cytotoxicity against normal human fibroblasts (BJ) and immortalized keratinocytes (HaCaT). STATEMENT OF SIGNIFICANCE:
The research is relevant for the potential uses of polyurethane films made from commercial raw materials as general medical supplies.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poliuretanos
/
Teste de Materiais
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Queratinócitos
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Isocianatos
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Fibroblastos
/
Membranas Artificiais
Limite:
Humans
Idioma:
En
Revista:
Mater Sci Eng C Mater Biol Appl
Ano de publicação:
2018
Tipo de documento:
Article
País de publicação:
HOLANDA
/
HOLLAND
/
NETHERLANDS
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NL
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PAISES BAJOS
/
THE NETHERLANDS