Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS<i>607</i>-family transposition.

Chen, Wenyang; Mandali, Sridhar; Hancock, Stephen P; Kumar, Pramod; Collazo, Michael; Cascio, Duilio; Johnson, Reid C

Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition.

Chen, Wenyang; Mandali, Sridhar; Hancock, Stephen P; Kumar, Pramod; Collazo, Michael; Cascio, Duilio; Johnson, Reid C.

Afiliação

Chen W; Department of Biological Chemistry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, United States.
Mandali S; Department of Biological Chemistry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, United States.
Hancock SP; Department of Biological Chemistry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, United States.
Kumar P; Department of Biological Chemistry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, United States.
Collazo M; Department of Energy Institute of Genomics and Proteomics, University of California at Los Angeles, Los Angeles, United States.
Cascio D; Department of Energy Institute of Genomics and Proteomics, University of California at Los Angeles, Los Angeles, United States.
Johnson RC; Department of Biological Chemistry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, United States.

Elife ; 72018 10 05.

Article em En | MEDLINE | ID: mdl-30289389

Assuntos

Elementos de DNA Transponíveis/genética; DNA/genética; Mutagênese Insercional; Transposases/genética; Absorciometria de Fóton; Bactérias/genética; DNA/química; DNA/metabolismo; DNA Bacteriano/genética; DNA Bacteriano/metabolismo; Modelos Moleculares; Conformação de Ácido Nucleico; Ligação Proteica; Multimerização Proteica; Estrutura Quaternária de Proteína; Recombinases/química; Recombinases/genética; Recombinases/metabolismo; Serina/metabolismo; Transposases/química; Transposases/metabolismo

Palavras-chave

DNA transposition; E. coli; Helicobacter pylori; Mycobacteria tuberculosis; Sulfolobus islandicus; biochemistry; chemical biology; chromosomes; gene expression; nucleoprotein complex; serine recombinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Elementos de DNA Transponíveis / Mutagênese Insercional / Transposases Idioma: En Revista: Elife Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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