The anticoagulant effect of dabigatran is reflected in the lag time and time-to-peak, but not in the endogenous thrombin potential or peak, of thrombin generation.

Bloemen, Saartje; Zwaveling, Suzanne; Douxfils, Jonathan; Roest, Mark; Kremers, Romy; Mullier, François

Bloemen, Saartje; Zwaveling, Suzanne; Douxfils, Jonathan; Roest, Mark; Kremers, Romy; Mullier, François.

Afiliação

Bloemen S; Synapse Research Institute, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address
Zwaveling S; Synapse Research Institute, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
Douxfils J; Department of Pharmacy, Namur Research Institute for Life Sciences, University of Namur, Namur, Belgium.
Roest M; Synapse Research Institute, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
Kremers R; Synapse Research Institute, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
Mullier F; Université catholique de Louvain, CHU UCL Namur, Namur Thrombosis and Hemostasis Center, Hematology Laboratory, Namur, Belgium.

Thromb Res ; 171: 160-166, 2018 11.

Article em En | MEDLINE | ID: mdl-30316961

Assuntos

Antitrombinas/farmacologia; Coagulação Sanguínea/efeitos dos fármacos; Dabigatrana/farmacologia; Trombina/metabolismo; Antitrombinas/sangue; Testes de Coagulação Sanguínea/métodos; Calibragem; Dabigatrana/sangue; Humanos; Trombina/análise

Palavras-chave

Anticoagulant; Dabigatran; Idarucizumab; Thrombin generation

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Trombina / Antitrombinas / Dabigatrana Limite: Humans Idioma: En Revista: Thromb Res Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google