Enantioselective analysis of pheniramine in rat using large volume sample stacking or cation-selective exhaustive injection and sweeping coupled with cyclodextrin modified electrokinetic chromatography.

Yao, Yaqi; Zhang, Bo; Li, Shuang; Yu, Jia; Guo, Xingjie

Yao, Yaqi; Zhang, Bo; Li, Shuang; Yu, Jia; Guo, Xingjie.

Afiliação

Yao Y; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, PR China.
Zhang B; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, PR China.
Li S; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, PR China.
Yu J; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, PR China. Electronic address: yujia_yc@163.com.
Guo X; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, PR China. Electronic address: gxjhyz@gmail.com.

Talanta ; 192: 226-232, 2019 Jan 15.

Article em En | MEDLINE | ID: mdl-30348382

Assuntos

Cromatografia/métodos; Feniramina/sangue; Administração Oral; Animais; Soluções Tampão; Masculino; Feniramina/administração & dosagem; Feniramina/química; Feniramina/farmacocinética; Fosfatos/química; Ratos Wistar; Estereoisomerismo; beta-Ciclodextrinas/química

Palavras-chave

CSEI-sweeping-CDEKC; Enantioseparation; LVSS-sweeping-CDEKC; Pheniramine enantiomers; Plasma protein binding; Stereoselective pharmacokinetic study

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Feniramina / Cromatografia Limite: Animals Idioma: En Revista: Talanta Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

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