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Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.
Maher, Geoffrey J; Ralph, Hannah K; Ding, Zhihao; Koelling, Nils; Mlcochova, Hana; Giannoulatou, Eleni; Dhami, Pawan; Paul, Dirk S; Stricker, Stefan H; Beck, Stephan; McVean, Gilean; Wilkie, Andrew O M; Goriely, Anne.
Afiliação
  • Maher GJ; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Ralph HK; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Ding Z; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Koelling N; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Mlcochova H; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Giannoulatou E; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Dhami P; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Paul DS; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Stricker SH; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Beck S; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • McVean G; Clinical Genetics Group, MRC-Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Wilkie AOM; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.
  • Goriely A; Medical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, United Kingdom.
Genome Res ; 28(12): 1779-1790, 2018 12.
Article em En | MEDLINE | ID: mdl-30355600
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Transdução de Sinais / Proteínas ras / Proteínas Quinases Ativadas por Mitógeno / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Transdução de Sinais / Proteínas ras / Proteínas Quinases Ativadas por Mitógeno / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos