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Platelet-rich plasma to rescue an ulcerated orbital dermal fat graft.
Chaparro Tapias, Tania Andrea; Díaz Díaz, Alberto Luis; Secondi, Roberto; Coy Villamil, Helena; Sánchez España, Juan Carlos.
Afiliação
  • Chaparro Tapias TA; Fundaciόn Oftalmolόgica de Santander (FOSCAL), Bucaramanga, Colombia.
  • Díaz Díaz AL; Fundaciόn Oftalmolόgica de Santander (FOSCAL), Bucaramanga, Colombia.
  • Secondi R; Facolta di Medicina e Psicologia, Universita degli Studi di Roma La Sapienza, Rome, Italy.
  • Coy Villamil H; Fundaciόn Oftalmolόgica de Santander (FOSCAL), Bucaramanga, Colombia.
  • Sánchez España JC; Oculoplastic Unit, General Hospital of Granollers, Granollers, Spain.
Eur J Ophthalmol ; 29(6): 654-658, 2019 Nov.
Article em En | MEDLINE | ID: mdl-30360664
INTRODUCTION: Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft. METHODS: Three patients, who had undergone autologous dermal fat graft to treat their anophthalmic socket, were given a 2-mL subconjunctival platelet-rich plasma injection in the exposed graft margins. Demographic and clinical features, treatment protocol, clinical course, complications and follow-up time are reported. In the preoperative examination, all the patients presented a primary epithelial defect of the dermal fat graft. RESULTS: There were no major complications such as necrosis or infection. One patient presented a small conjunctival granuloma at 1-month follow up. Mean postoperative follow-up duration was 13 (range: 10-16) months. By 1 month, the chronic epithelial defect had resolved with the graft integrated within the orbital tissues in all cases. All patients were referred for artificial prosthesis placement. CONCLUSION: Although further work is needed, our findings suggest that a single subconjunctival platelet-rich plasma injection could be an effective, safe and economic alternative to surgery to rescue an ulcerated orbital dermal fat graft.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Orbitárias / Úlcera / Tecido Adiposo / Implantes Orbitários / Plasma Rico em Plaquetas Tipo de estudo: Etiology_studies / Guideline Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Orbitárias / Úlcera / Tecido Adiposo / Implantes Orbitários / Plasma Rico em Plaquetas Tipo de estudo: Etiology_studies / Guideline Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos