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Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.
Teumer, Alexander; Chaker, Layal; Groeneweg, Stefan; Li, Yong; Di Munno, Celia; Barbieri, Caterina; Schultheiss, Ulla T; Traglia, Michela; Ahluwalia, Tarunveer S; Akiyama, Masato; Appel, Emil Vincent R; Arking, Dan E; Arnold, Alice; Astrup, Arne; Beekman, Marian; Beilby, John P; Bekaert, Sofie; Boerwinkle, Eric; Brown, Suzanne J; De Buyzere, Marc; Campbell, Purdey J; Ceresini, Graziano; Cerqueira, Charlotte; Cucca, Francesco; Deary, Ian J; Deelen, Joris; Eckardt, Kai-Uwe; Ekici, Arif B; Eriksson, Johan G; Ferrrucci, Luigi; Fiers, Tom; Fiorillo, Edoardo; Ford, Ian; Fox, Caroline S; Fuchsberger, Christian; Galesloot, Tessel E; Gieger, Christian; Gögele, Martin; De Grandi, Alessandro; Grarup, Niels; Greiser, Karin Halina; Haljas, Kadri; Hansen, Torben; Harris, Sarah E; van Heemst, Diana; den Heijer, Martin; Hicks, Andrew A; den Hollander, Wouter; Homuth, Georg; Hui, Jennie.
Afiliação
  • Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany. ateumer@uni-greifswald.de.
  • Chaker L; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany. ateumer@uni-greifswald.de.
  • Groeneweg S; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.
  • Li Y; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Di Munno C; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Barbieri C; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.
  • Schultheiss UT; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Traglia M; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
  • Ahluwalia TS; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.
  • Akiyama M; Department of Science and Technologies, University of Sannio, Benevento, Italy.
  • Appel EVR; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
  • Arking DE; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
  • Arnold A; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
  • Astrup A; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
  • Beekman M; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Beilby JP; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Bekaert S; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Boerwinkle E; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Brown SJ; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • De Buyzere M; Department of Nutrition, Exercise, and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Campbell PJ; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
  • Ceresini G; Pathwest Laboratory Medicine WA, Nedlands, WA, 6009, Australia.
  • Cerqueira C; School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
  • Cucca F; Bimetra, Clinical Research Center Ghent, Ghent University Hospital, Ghent, Belgium.
  • Deary IJ; Human Genetics Center, University of Texas Health Science Center, 1200 Pressler Street, Houston, TX, 77030, USA.
  • Deelen J; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.
  • Eckardt KU; Department of Cardiology, Ghent University Hospital, Ghent, Belgium.
  • Ekici AB; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.
  • Eriksson JG; Department of Medicine and Surgery, University of Parma, University Hospital of Parma, Parma, Italy.
  • Ferrrucci L; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.
  • Fiers T; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.
  • Fiorillo E; Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, Italy.
  • Ford I; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Fox CS; Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Fuchsberger C; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
  • Galesloot TE; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Gieger C; Department of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany.
  • Gögele M; Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • De Grandi A; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Grarup N; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Greiser KH; Folkhälsan Research Center, Helsinki, Finland.
  • Haljas K; National Institute for Health and Welfare, Helsinki, Finland.
  • Hansen T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
  • Harris SE; Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium.
  • van Heemst D; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.
  • den Heijer M; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
  • Hicks AA; National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA, USA.
  • den Hollander W; Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Homuth G; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy.
  • Hui J; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Nat Commun ; 9(1): 4455, 2018 10 26.
Article em En | MEDLINE | ID: mdl-30367059
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hormônios Tireóideos / Tireotropina / Regulação da Expressão Gênica / 2-Aminoadipato Transaminase / Proteínas Cotransportadoras de Sódio-Fosfato Tipo I Tipo de estudo: Etiology_studies / Prognostic_studies / Systematic_reviews Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hormônios Tireóideos / Tireotropina / Regulação da Expressão Gênica / 2-Aminoadipato Transaminase / Proteínas Cotransportadoras de Sódio-Fosfato Tipo I Tipo de estudo: Etiology_studies / Prognostic_studies / Systematic_reviews Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido