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Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles.
Friedrich, Jillian; Kordasiewicz, Holly B; O'Callaghan, Brennon; Handler, Hillary P; Wagener, Carmen; Duvick, Lisa; Swayze, Eric E; Rainwater, Orion; Hofstra, Bente; Benneyworth, Michael; Nichols-Meade, Tessa; Yang, Praseuth; Chen, Zhao; Ortiz, Judit Perez; Clark, H Brent; Öz, Gülin; Larson, Sarah; Zoghbi, Huda Y; Henzler, Christine; Orr, Harry T.
Afiliação
  • Friedrich J; Institute for Translational Neuroscience and.
  • Kordasiewicz HB; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • O'Callaghan B; Ionis Pharmaceuticals, Carlsbad, California, USA.
  • Handler HP; Institute for Translational Neuroscience and.
  • Wagener C; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Duvick L; Institute for Translational Neuroscience and.
  • Swayze EE; Graduate Program in Neuroscience.
  • Rainwater O; Institute for Translational Neuroscience and.
  • Hofstra B; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Benneyworth M; Institute for Translational Neuroscience and.
  • Nichols-Meade T; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Yang P; Ionis Pharmaceuticals, Carlsbad, California, USA.
  • Chen Z; Institute for Translational Neuroscience and.
  • Ortiz JP; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Clark HB; Institute for Translational Neuroscience and.
  • Öz G; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Larson S; Department of Neuroscience, and.
  • Zoghbi HY; Department of Neuroscience, and.
  • Henzler C; Institute for Translational Neuroscience and.
  • Orr HT; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
JCI Insight ; 3(21)2018 11 02.
Article em En | MEDLINE | ID: mdl-30385727
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Doenças Neurodegenerativas / Ataxias Espinocerebelares / Ataxina-1 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: JCI Insight Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Doenças Neurodegenerativas / Ataxias Espinocerebelares / Ataxina-1 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: JCI Insight Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos