Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-ß and TRAIL and suppress the growth of H460 human lung cancer cells.

Jung, Pil Young; Ryu, Hoon; Rhee, Ki-Jong; Hwang, Soonjae; Lee, Chang Gun; Gwon, Sun-Yeong; Kim, Jiye; Kim, Juwon; Yoo, Byung-Su; Baik, Soon Koo; Bae, Keum Seok; Eom, Young Woo

Jung, Pil Young; Ryu, Hoon; Rhee, Ki-Jong; Hwang, Soonjae; Lee, Chang Gun; Gwon, Sun-Yeong; Kim, Jiye; Kim, Juwon; Yoo, Byung-Su; Baik, Soon Koo; Bae, Keum Seok; Eom, Young Woo.

Afiliação

Jung PY; Department of General Surgery, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Ryu H; Department of General Surgery, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Rhee KJ; Department of Biomedical Laboratory Science, Yonsei University College of Health Sciences, Wonju, 26493, South Korea.
Hwang S; Department of Biomedical Laboratory Science, Yonsei University College of Health Sciences, Wonju, 26493, South Korea.
Lee CG; Department of Biomedical Laboratory Science, Yonsei University College of Health Sciences, Wonju, 26493, South Korea.
Gwon SY; Department of Biomedical Laboratory Science, Yonsei University College of Health Sciences, Wonju, 26493, South Korea.
Kim J; Department of Plastic and Reconstructive Surgery, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Kim J; Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Yoo BS; Cell Therapy and Tissue Engineering Center, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Baik SK; Cell Therapy and Tissue Engineering Center, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea.
Bae KS; Department of General Surgery, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea. Electronic address: bksgs@yonsei.ac.kr.
Eom YW; Cell Therapy and Tissue Engineering Center, Yonsei University Wonju College of Medicine, Wonju, 26426, South Korea. Electronic address: yweom@yonsei.ac.kr.

Cancer Lett ; 440-441: 202-210, 2019 01.

Article em En | MEDLINE | ID: mdl-30393160

Assuntos

Interferon beta/biossíntese; Neoplasias Pulmonares/terapia; Células-Tronco Mesenquimais/metabolismo; Ligante Indutor de Apoptose Relacionado a TNF/biossíntese; Adulto; Animais; Processos de Crescimento Celular/fisiologia; Linhagem Celular Tumoral; Xenoenxertos; Humanos; Interferon beta/genética; Interferon beta/farmacologia; Neoplasias Pulmonares/patologia; Transplante de Células-Tronco Mesenquimais; Células-Tronco Mesenquimais/citologia; Células-Tronco Mesenquimais/efeitos dos fármacos; Camundongos; Camundongos Nus; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ligante Indutor de Apoptose Relacionado a TNF/genética; Ligante Indutor de Apoptose Relacionado a TNF/farmacologia; Adulto Jovem

Palavras-chave

Adipose tissue-derived mesenchymal stem cells; IFN-ß; Lung cancer; Necrotic cell death; TRAIL

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon beta / Ligante Indutor de Apoptose Relacionado a TNF / Células-Tronco Mesenquimais / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Coréia do Sul País de publicação: Irlanda

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