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Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.
Platnich, Jaye M; Chung, Hyunjae; Lau, Arthur; Sandall, Christina F; Bondzi-Simpson, Adom; Chen, Huey-Miin; Komada, Takanori; Trotman-Grant, Aaron C; Brandelli, Jeremy R; Chun, Justin; Beck, Paul L; Philpott, Dana J; Girardin, Stephen E; Ho, May; Johnson, Roger P; MacDonald, Justin A; Armstrong, Glen D; Muruve, Daniel A.
Afiliação
  • Platnich JM; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Chung H; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Lau A; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Sandall CF; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
  • Bondzi-Simpson A; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Chen HM; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
  • Komada T; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Trotman-Grant AC; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Brandelli JR; Department of Microbiology, Immunology & Infectious Diseases, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Chun J; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Beck PL; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Philpott DJ; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Girardin SE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Ho M; Department of Microbiology, Immunology & Infectious Diseases, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Johnson RP; Public Health Agency of Canada, National Microbiology Laboratory, Guelph, ON, Canada.
  • MacDonald JA; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
  • Armstrong GD; Department of Microbiology, Immunology & Infectious Diseases, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
  • Muruve DA; Department of Medicine, University of Calgary, Calgary, AB, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada. Electronic address: dmuruve@ucalgary.ca.
Cell Rep ; 25(6): 1525-1536.e7, 2018 11 06.
Article em En | MEDLINE | ID: mdl-30404007
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Espécies Reativas de Oxigênio / Toxina Shiga / Caspases Iniciadoras / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Mitocôndrias / Proteínas de Neoplasias Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Espécies Reativas de Oxigênio / Toxina Shiga / Caspases Iniciadoras / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Mitocôndrias / Proteínas de Neoplasias Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá País de publicação: Estados Unidos