Two new tetralone glycosides from the green walnut husks of Juglans mandshurica Maxim.
Nat Prod Res
; 33(20): 2932-2938, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-30417677
ABSTRACT
Two new tetralone glycosides, 4(S)-5-methoxy juglanoside A (1), 4(S)-5-methoxy juglanoside D (2), together with ten known compounds (3-12) have been isolated from the green walnut husks of Juglans mandshurica Maxim. Their structures were elucidated on the basis of their ESI-MS, 1 D and 2 D NMR spectroscopic data. In addition, all compounds were evaluated for their cytotoxic activities against the cancer BGC-823 (human gastric carcinoma), HCT-15 (human colorectal carcinoma) and K562 (human chronic myeloid leukemia) cell lines. The results showed aglycones of naphthoquinones had stronger cytotoxic activities than glycosides of tetralone.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Juglans
/
Detecção Precoce de Câncer
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Glicosídeos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China