Effects of cholecalciferol supplementation on inflammatory markers and muscle damage indices of soccer players after a simulated soccer match.
Nutrition
; 59: 37-43, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30419498
ABSTRACT
OBJECTIVES:
Soccer-induced muscle damage and inflammation lead to a reduction in athletic performance. The aim of this study was to determine whether supplementation with cholecalciferol would reduce inflammation and muscle damage in soccer players after a simulated soccer match.METHODS:
Twenty-two soccer players (median age 27 y, interquartile range 5 y) were divided randomly into two groups, as follows a cholecalciferol group (n = 11) and a placebo group (n = 11). Cholecalciferol supplements (50 000 IU/wk) or placebos were administered to the groups by an independent co-worker. After 8 wk, the athletes participated in a simulated soccer match, and perceived exertion and heart rates were measured during the trial. Blood samples were obtained presupplementation, postsupplementation, immediately after, and 2- and 24-h postexercise for measurement of lactate dehydrogenase, creatine phosphokinase, C-reactive protein (CRP), and interleukin (IL)-6.RESULTS:
The intervention group demonstrated a significant increase in serum 25-hydroxyvitamin D levels (53.93, 10.68 ng/mL, P < 0.0001), which is the best indicator of vitamin D levels in the body, with no change in the circulating markers of muscle damage and CRP (P Ë 0.05) but showed increased IL-6 (Pâ¯=â¯0.034). In addition, the ratings of perceived exertion and heart rates were not altered by vitamin D compared with placebo ingestion (Pâ¯=â¯0.155 versus Pâ¯=â¯0.261; Pâ¯=â¯0.600 versus Pâ¯=â¯0.983).CONCLUSION:
The study showed that 50 000 IU/wk of cholecalciferol supplementation for 8 wk increased the 25-hydroxyvitamin D levels, with no effect on muscle damage indices or CRP. However, The IL-6 concentration was generally higher in the intervention group.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Futebol
/
Vitaminas
/
Colecalciferol
/
Músculo Esquelético
/
Mediadores da Inflamação
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Nutrition
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Irã