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Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors.
Ratnaparkhe, Manasi; Wong, John K L; Wei, Pei-Chi; Hlevnjak, Mario; Kolb, Thorsten; Simovic, Milena; Haag, Daniel; Paul, Yashna; Devens, Frauke; Northcott, Paul; Jones, David T W; Kool, Marcel; Jauch, Anna; Pastorczak, Agata; Mlynarski, Wojciech; Korshunov, Andrey; Kumar, Rajiv; Downing, Susanna M; Pfister, Stefan M; Zapatka, Marc; McKinnon, Peter J; Alt, Frederick W; Lichter, Peter; Ernst, Aurélie.
Afiliação
  • Ratnaparkhe M; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ); Faculty of Biosciences, Heidelberg University Germany, Heidelberg, 69120, Germany.
  • Wong JKL; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Wei PC; Boston Children's Hospital, Howard Hughes Medical Institute and Department of Genetics, Harvard Medical School, Boston, 02115, MA, USA.
  • Hlevnjak M; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Kolb T; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Simovic M; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ); Faculty of Biosciences, Heidelberg University Germany, Heidelberg, 69120, Germany.
  • Haag D; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, 69120, Germany.
  • Paul Y; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Devens F; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Northcott P; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Jones DTW; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, 38105-3678, United States.
  • Kool M; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, 69120, Germany.
  • Jauch A; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, 69120, Germany.
  • Pastorczak A; Institute of Human Genetics, University of Heidelberg, Heidelberg, 69120, Germany.
  • Mlynarski W; Department of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Lodz, 91-738, Poland.
  • Korshunov A; Department of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Lodz, 91-738, Poland.
  • Kumar R; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Department of Neuropathology, Heidelberg University Hospital and German Cancer Consortium (DKTK), Heidelberg, 69120, Germany.
  • Downing SM; Division of Molecular Genetic Epidemiology; German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center, Heidelberg, 69120, Germany.
  • Pfister SM; Department of Genetics, St. Jude Children's Research Hospital, Memphis, 38105-3678, TN, USA.
  • Zapatka M; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, 69120, Germany.
  • McKinnon PJ; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Alt FW; Department of Genetics, St. Jude Children's Research Hospital, Memphis, 38105-3678, TN, USA.
  • Lichter P; Boston Children's Hospital, Howard Hughes Medical Institute and Department of Genetics, Harvard Medical School, Boston, 02115, MA, USA.
  • Ernst A; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Nat Commun ; 9(1): 4760, 2018 11 12.
Article em En | MEDLINE | ID: mdl-30420702
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias Encefálicas / Genoma / Reparo do DNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias Encefálicas / Genoma / Reparo do DNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido