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PPARγ-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development.
Tanis, Steven P; Colca, Jerry R; Parker, Timothy T; Artman, Gerald D; Larsen, Scott D; McDonald, William G; Gadwood, Robert C; Kletzien, Rolf F; Zeller, James B; Lee, Pil H; Adams, Wade J.
Afiliação
  • Tanis SP; SPTanis PharmaChem Consulting LLC, Carlsbad, CA 92011, United States. Electronic address: sptanis@sbcglobal.net.
  • Colca JR; Metabolic Solutions Development Co., Kalamazoo, MI 49007, United States; Cirius Therapeutics, San Diego, CA 92130, United States.
  • Parker TT; Kalexsyn, Kalamazoo, MI 49008, United States.
  • Artman GD; Kalexsyn, Kalamazoo, MI 49008, United States.
  • Larsen SD; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States.
  • McDonald WG; Metabolic Solutions Development Co., Kalamazoo, MI 49007, United States; Cirius Therapeutics, San Diego, CA 92130, United States.
  • Gadwood RC; Kalexsyn, Kalamazoo, MI 49008, United States.
  • Kletzien RF; Metabolic Solutions Development Co., Kalamazoo, MI 49007, United States; Cirius Therapeutics, San Diego, CA 92130, United States.
  • Zeller JB; Jim Zeller Consulting, Scottsdale AZ 85259, United States.
  • Lee PH; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States.
  • Adams WJ; ADaMET Consulting LLC, Kalamazoo, MI 49008, United States.
Bioorg Med Chem ; 26(22): 5870-5884, 2018 12 01.
Article em En | MEDLINE | ID: mdl-30429097
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Desenho de Fármacos / Tiazolidinedionas / PPAR gama Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Desenho de Fármacos / Tiazolidinedionas / PPAR gama Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article